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Description
Nivolumab biosimilar is a human monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. Nivolumab is an IgG4 kappa immunoglobulin that has a calculated molecular mass of 146 kDa. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line.
Nivolumab biosimilar is supplied at a concentration of 10 mg/mL as a sterile, preservative-free, non-pyrogenic, clear to opalescent, colorless to pale-yellow liquid, which contains 30 mg/mL mannitol, 0.008 mg/mL pentetic acid, 0.2 mg/mL polysorbate 80, 2.92 mg/mL sodium chloride, 5.88 mg/mL sodium citrate dihydrate, and Water for Injection. May contain hydrochloric acid and/or sodium hydroxide to adjust pH to 6.
Statement: this product is used for R&D only, not for clinical usage.
Properties
Name
|
Nivolumab biosimilar
|
CAS
NO.
|
946414-94-4
|
Type
|
Whole
antibody
|
Source
|
Human
|
Target
|
PD-1
|
Clone
|
Monoclone
|
Molecular
Weight
|
146 kDa
|
Formula
|
C6362H9862N1712O1995S42
|
Antibody
Form
|
Purified immunoglobulin
|
Physical
Form
|
Solution
|
Grade
Standard
|
Medicine Grade
|
Place
of Origin
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China(Mainland)
|
Storage
|
-70±15℃ for long-term
storage, 2-8℃ for short-term storage, away from light.
|
Supply Ability
20 kilogram per year, Minimum order quantity is 1 gram.
Price
Inquiry
Material Safety Data Sheet
If you need more information, please contact us.
Certificate Of Analysis
/en/UploadFile/file/201805/20180508154434633463.rar
Detail information about the product please refer the website below:
https://en.wikipedia.org/wiki/Nivolumab
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